The only PMS and PMDD supplement backed by its own human clinical trial

Why did we conduct a clinical trial?

Our formula is based on 100+ clinical trials of ingredients in PMS, PMDD and period pain.

But we didn't stop there.

Study Details

Participants

  • 40 women aged 18-45
  • Baseline symptom severity was moderate to severe (3/4)
  • Naturally cycling (85%) or on hormonal contraception (15%)

Intervention

  • Daily supplementation for 3 menstrual cycles
  • Questionnaires filled out each cycle
  • We conducted an independent clinical trial specifically on DITTO Cycle Supplement to ensure our complete formula, not just the individual ingredients, delivers the results you deserve.
By Cycle 3 of the Clinical Trial:
88%

Had reduced overall severity of symptoms

82%

Had reduced duration of symptoms

Reported relief from both mental and physical symptoms

88%

Had fewer mood changes

91%

Had reduced period cramps

82%

Had improved mood

The validated Menstrual Symptom Questionnaire (MSQ) score was significantly reduced at Cycle 1 (P=0.0028), Cycle 2 (P<0.0001), and Cycle 3 (P<0.0001)

Benefits build progressively from Cycle 1 to Cycle 3

  • Symptom severity dropped from an average of 3/4 (distracting) at baseline, to 1/4 (barely noticeable) at Cycle 3.

Participants rated symptom severity on this scale:

  1. Severe
  2. Distracting
  3. Moderate
  4. Barely noticeable
  5. Not noticeable
Select a symptom to see impact between Cycle 1 and Cycle 3

More likely to experience benefits over time

Select a symptom example to see the build between Cycle 1 and Cycle 3

& 9 more symptoms

94%

Wanted to continue taking the Cycle Supplement after the trial

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To support anyone with cycle symptoms

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Will DITTO work if I’m on hormonal contraception?

  • We know that many on hormonal contraception continue to have symptoms, so we conducted a sub-analysis on this, as well.
By Cycle 3, for women on hormonal contraception:
83%

Had reduced overall severity of symptoms

83%

Had reduced duration of symptoms

Nutrients with No Nonsense

Every nutrient within our capsule shows statistically significant effects for reducing menstrual cycle symptoms. 

MEET OUR NUTRIENTS