Cycle Supplement

This clinically validated daily supplement is formulated to reduce every menstrual cycle symptom.

10 nutrients, proven by the highest quality of clinical trials.
Advanced biotechnology beadlets for maximum absorption.
For anyone with cycle symptoms, incl. those with PMS, PMDD, PCOS, endometriosis, or in perimenopause. Suitable if on contraception.

Take for at least 3 months for full benefits, though many feel results in weeks.

Product variants

Reduces Cravings
Reduces Cramps
Improves Energy
Improves Mood
Reduces Bloating
Reduces Breast Tenderness
Reduces Headaches
Reduces Anxiety
Reduces Irritability

Formulated by leading female scientists

Learn more

Formulated by leading female scientists

Alice specialises in evidence-based nutrition, laboratory work and clinical trials. With a strong dedication to the highest standards of science, she translates clinical trial findings into effective solutions for her DITTO community.

Alice van der Schoot

Nutrition Scientist & Founder

Dr. Anita Mitra is a gynaecologist with 10+ years NHS experience, specialising in surgery for gynaecological cancers and treating conditions like fibroids, PCOS, and endometriosis. Known online as 'The Gynae Geek' (also the title of her first book), she is the author of Dealing with Problem Periods. She holds a PhD from Imperial College London.

Dr Anita Mitra (Gynae Geek)

OB-GYN & Medical Advisor

Dr Tosin brings over a decade of clinical experience across the NHS and private health sector, with a particular focus in Women’s Health. She has been featured in a number of publications and is an advisory mentor for FemTech Lab.

Dr Tosin Sotubo-Ajayi

GP & Medical Advisor

Menstrual health,
matters

Bringing our bodies and minds into their best state to manage our symptoms.

MOOD

Omega-3, Vitamin B6, Saffron & Chamomile improve mood and maintain normal brain health.

ENERGY LEVELS

Iron reduces tiredness and fatigue and is essential for oxygen transport. Vitamin C increases the absorption of Iron.

BLOATING

Magnesium reduces water retention by regulating electrolyte balance.

PAINFUL CRAMPS

Vitamin D reduces prostaglandins and inflammation, Zinc reduces oxidative stress and Magnesium relaxes smooth muscles of the uterus.

CRAVINGS

Chromium helps reduce cravings by stabilising blood sugar levels and improving insulin sensitivity.

BREAST TENDERNESS

Magnesium reduces water retention by regulating electrolyte balance, helping alleviate swelling and tenderness.

HEADACHES

Magnesium reduces headaches by preventing the constriction of blood vessels.

Nutrient Delivery Biotechnology

Did you know? In standard supplements, when nutrients are released all at once, they can actually block each other's absorption.

Engineered for Maximum Absorption

The technology allows timed and targeted release of different nutrients, reducing interference.

Developed for Steady Release

Avoids overwhelming the body's absorption mechanisms, ensuring more is absorbed over time.

Kind to your Body

Infused with citrus flavour and gentle on your gut, taking the capsules is an enjoyable experience.

Simplified Routine

It combines oil and dry ingredients, meaning that you no longer need multiple supplements.

See our technology

Ingredients with Impact

Researched and tested. Nothing but the best when it comes to your menstrual health.

Magnesium

Magnesium Bisglycinate

Chromium

Chromium Picolinate

Iron

Ferrous Bisglycinate

Chamomile

Chamomile Oil

Omega 3 DHA & EPA

Algal Oil

Vitamin B6

Pyridoxal-5-Phosphate

Vitamin C

Ascorbic Acid

Saffron

Crocus Sativus L.

Vitamin D3

Cholecalciferol

Zinc

Zinc Citrate

Magnesium

Magnesium helps to relax muscles, reducing painful cramps and body aches. It is also an electrolyte that helps regulate the body’s fluid balance, reducing water-retention related symptoms such as breast tenderness and bloating. Magnesium Bisglycinate is one of the most highly bioavailable forms. It is chelated, meaning “bound” to the amino acid glycine, which helps it pass more easily through the gut wall.

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Chromium

Chromium is a vital trace mineral that helps regulate blood glucose levels by enhancing the action of insulin, the hormone involved in managing how your body processes and stores glucose and fat. Chromium is integral to metabolism, which is why it’s supplemented to combat cravings and improve insulin resistance. Chromium Picolinate is a highly absorbable form that is well studied.

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Iron

Ferrous bisglycinate is a highly bioavailable form of iron which is effective for restoring iron levels in between monthly bleeds. It is also gentle on the stomach. This is because it’s chelated, meaning “bound” to the amino acid glycine, helping it pass more easily through the gut wall. Iron is essential for haemoglobin production in red blood cells, improving oxygen transport throughout the body and reducing tiredness and fatigue.

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Chamomile

Chamomile oil contains a flavanoid (plant compound) called apigenin, which crosses the blood-brain barrier and interacts with GABA receptors to reduce anxiety and irritability. As a concentrated form, the oil works quickly and is ideal for fast relief.

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Omega 3 DHA & EPA

Omega-3s improve brain cell membrane fluidity, optimising neurotransmitter activity and reducing anger and low mood. They also help to decrease the production of pro-inflammatory substances including prostaglandins, leading to less pain and discomfort from menstrual cramps.
Algal oil is a sustainable source of omega-3s, avoiding overfishing and supporting vegan and eco-friendly choices.

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Vitamin B6

P5P, the active form of Vitamin B6, is a cofactor in over 100 enzymatic reactions. It is an essential for the biosynthesis of the neurotransmitters dopamine, serotonin and GABA, which have direct impacts on mood regulation. It is also required for haemoglobin production in red blood cells, improving oxygen transport throughout the body.

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Vitamin C

Vitamin C, in its pure form as Ascorbic Acid, plays several essential roles in maintaining your body’s overall health. It is important for immune health, collagen production and antioxidant protection. It also enhances iron absorption, helping prevent iron deficiency anaemia.

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Saffron

Saffron enhances mood with bioactive compounds, safranal and crocin, which inhibit the re-uptake of serotonin and dopamine, meaning more of these feel-good chemicals in your brain.

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Vitamin D3

Vitamin D3 lowers prostaglandins, the chemical messengers that are responsible for painful cramps. It also helps to reduce inflammatory cytokines. Its superior bioavailability compared to D2 ensures efficient absorption and enhanced effectiveness for overall well-being.

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Zinc

Zinc is an essential mineral, with Zinc Citrate offering excellent absorption. Zinc is an antioxidant, so it fights oxidative stress, ultimately reducing cell damage and inflammation that contributes to period pain. it also zinc increases brain-derived neurotrophic factor (BDNF), a protein that is key to the brain's neurobiology, helping to improve emotional regulation.

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Bio-based Packaging

Plastic-free Packaging

The purpose of our packaging is to reduce plastic pollution by offering a sustainable alternative to conventional plastic. Our jars are made of responsibly sourced plant-based and biodegradable binders, and sustainable composition like wood from industrial side streams or naturally occurring clay minerals.

Sustainably Sourced Raw Materials

Our jars use a selection of biopolymers and natural fibres with the aim to maximise the use of recycled content, side streams, and certified biomasses. We make sure that the biomasses from which our biopolymers originate are sustainably grown according to good land use principles. Our leading design principle is to mimic nature.

Biodegradable & Compostable

One way to recycle biodegradable materials is through organic recycling, which includes composting and anaerobic digestion. All our jars and pouches can be digested by naturally occurring microorganisms. They biodegrade into CO2, water, and biomass in a similar time frame as tree leaves, and leave no permanent microplastics or toxic residues behind.

No Microplastics

Microplastics have been discovered in the highest peaks and the deepest seas. With an expected 300% growth in plastic production by 2050, the amount of microplastics in our environment is only escalating. The only way to stop microplastic pollution is to replace conventional plastic with bio-based and biodegradable materials.

Frequently Asked Questions

Who is the Cycle Supplement for?

This supplement is formulated based on clinical trials focused on reducing symptoms in people who suffer from mild to severe menstrual cycle symptoms - whether it be premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), dysmenorrhea (painful cramps), endometriosis or polycystic ovary syndome (PCOS). It’s especially beneficial for those dealing with painful cramps, bloating, breast tenderness, headaches, menstrual migraines, fatigue, low energy, body aches, pelvic pain, cravings, mood swings, anxiety, irritability, and difficulty concentrating.

Additionally, it is beneficial for the erratic cycle symptoms during the perimenopause transition.

It’s also ideal for anyone looking to support their overall menstrual health or those whose energy levels or emotional well-being are affected by the ebb and flow of their menstrual cycle.

How should I take this supplement for best results?

Take 2 capsules together daily, with or without food, with a glass of water in the AM ⏰

How long before I notice the benefits?

To feel the full benefits of the supplement, it's recommended to take it daily for at least 3 full menstrual cycles. While many will experience benefits within the first few weeks, clinical trials often show modest effects during the first cycle, with more significant improvements felt during the 2nd and 3rd cycle of daily supplementation.

When taking nutrition supplements, it typically takes several weeks to feel noticeable effects because they need time to interact with your body’s ongoing cellular processes and support them optimally (e.g. energy metabolism and neurotransmitter production). Many nutrients work by building up in your body gradually, and need to be consistently present in your system for weeks before the effects become apparent, especially when correcting deficiencies and supporting long-term health ⏳

Why should I take this daily, and not just in the menstrual phase where I have symptoms?

Clinical trials show that to effectively reduce menstrual cycle symptoms, nutrients must be taken daily. By keeping your nutrient levels consistently optimal, you equip your body to handle any effects that come with hormonal shifts, reducing, or even preventing symptoms before they start. Nutrients need time to interact with the ongoing cellular processes underlying our symptoms, so taking the supplement only when symptoms arise is insufficient.

How do nutrients reduce menstrual cycle symptoms?

The hormonal shifts of our menstrual cycle trigger a wide range of cellular processes in the body, impacting things like neurotransmitter production, inflammation and oxidative stress. Nutrients don’t alter hormones, but instead they work by targeting these “intermediate” processes that occur between hormonal changes and your resulting symptoms. For instance, zinc helps support brain-derived neurotrophic factor (BDNF) which regulates the growth and plasticity of neural circuits that regulate emotions, and reduces oxidative stress; vitamin B6 is required for neurotransmitter biosynthesis that impacts mood (e.g. serotonin); while magnesium aids in regulating fluid balance and alleviating excess water retention, or relaxing the muscles that cause your cramps. This is how these nutrients can help manage the symptoms associated with hormonal fluctuations.

Why are there beadlets inside the supplement?

Well, did you know that in standard supplements, when many nutrients are released at the same time in our body, certain nutrients (like iron, zinc, magnesium) can actually block each other’s absorption?

But your DITTO supplement is designed with a nutrient delivery technology to maximise absorption:

Timed and targeted release of different nutrients: With these beadlets, each nutrient is sprayed on in layers and they get released gradually in your body, to avoid them inhibiting each other’s absorption.
Prevents “Vitamin Dumping”: This steady release also means you avoid “vitamin dumping”, which is when too much of a nutrient is released at once, leading to excess amounts being eliminated by the body without being absorbed. The gradual release avoids overwhelming the body's absorption mechanisms, ensuring that more of the nutrient is absorbed over time.

Why do my supplements smell and taste like oranges?

Meet the orange grove tab! Have you ever taken an omega-3 supplements and been hit with a fishy after taste? We really didn’t want that with our supplement, which contains algal oil omega-3. This is why we send them to you with a tab that is infused with a citrus scent, which makes taking them an enjoyable experience.

What makes this supplement scientifically-backed?

Each nutrient in our capsule is tested in randomised, placebo-controlled clinical trials, demonstrating statistically significant reductions in menstrual cycle symptoms compared to a placebo.

We prioritise quality over quantity by selecting only the most relevant studies focused on individuals suffering with symptoms specifically tied to their cycles. This ensures our supplement is specifically effective for those challenges.

To sum it up - every nutrient is scientifically proven to address menstrual cycle symptoms and the underlying mechanisms that contribute to them.

Will this work if I’m on hormonal contraception?

Many of us on hormonal contraception continue to experience breast tenderness, bloating, cramps, low energy, and mood changes - especially around the time of our withdrawal bleeds or pill breaks. This supplement is designed to be effective at addressing these same challenges you may still face!

Are there any potential side effects?

All the forms of the nutrients in this supplement are carefully selected for their gentle nature and are well-tolerated.

Which menstrual symptoms does this help with? What if I have conditions like endometriosis or PCOS?

Many of us experience the umbrella of PMS symptoms and painful periods alongside distinct symptoms originating from other menstrual conditions. DITTO reduces these, but also addresses condition-specific symptoms.

Every nutrient is proven to work for PMS and dysmenorrhea (painful cramps).

Scientific research also supports the effectiveness of key DITTO nutrients in managing symptoms specifically related to these conditions:

Endometriosis pelvic pain, dyspareunia, dysmenorrhea (through vitamin D, chamomile)
PCOS insulin sensitivity, follicular development, menstrual cycle regulation, hirsutism, cardiovascular risk factors (through vitamin D, zinc, magnesium, omega-3, chromium)
Fibroid size (through vitamin D)

So, DITTO offers relief for both general and condition-specific conditions, whether they occur separately or alongside each other!

Can I take this if I’m perimenopausal or menopausal?

Absolutely! This supplement can still help with menstrual cycle symptoms during perimenopause, and many of the nutrients it contains also support many aspects of overall health after menopause.

Is this supplement vegan-friendly?

Yes! Every ingredient is vegan.

What do you mean by 'bioavailable' ingredients?

‘Bioavailable’ ingredients are nutrients that your body can easily absorb and put to work. Not all nutrient forms are absorbed equally - some are used better than others. For example, your body might only absorb 20% of a certain nutrient form (like magnesium oxide), while with another one, it could be as high as 80% or more (like magnesium glycinate).

Can you tell me more about the sustainability of the brand (including the refill pots and pouches)?

Your pot is made from a material crafted from responsibly sourced raw materials, primarily wood-fibres and agricultural byproducts like crop residues that would typically be considered waste. By repurposing them, we’re helping reduce waste in landfills. It’s biodegradable and compostable, meaning it can be digested by naturally occurring microorganisms, leaving no microplastics or toxic load behind. The speckles come from the natural byproducts, giving the pot a beautiful earthy look and a ceramic-like feel.

Promotes a Circular Economy.
Biodegradable & Compostable.
Distinctive Texture.
Designed for Longevity.

Once you’ve got your pot for life, we’ll send you refill pouches that are compostable and letterbox-friendly. These convenient pouches fit right through your door, reducing the need for bulky packaging and cutting down on transportation emissions, ultimately lowering carbon footprints.

What’s the best way to store this supplement?

Store in in a cool, dry place away from direct sunlight and moisture.

Can I take this supplement while pregnant or breastfeeding?

It's always recommended to consult with your doctor before taking any supplements during pregnancy or while breastfeeding.

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Cycle Supplement

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Cycle Supplement

Formulated by leading female scientists

Formulated by leading female scientists

Menstrual health, matters

Bringing our bodies and minds into their best state to manage our symptoms.

MOOD

Omega-3, Vitamin B6, Saffron & Chamomile improve mood and maintain normal brain health.

ENERGY LEVELS

Iron reduces tiredness and fatigue and is essential for oxygen transport. Vitamin C increases the absorption of Iron.

BLOATING

Magnesium reduces water retention by regulating electrolyte balance.

PAINFUL CRAMPS

Vitamin D reduces prostaglandins and inflammation, Zinc reduces oxidative stress and Magnesium relaxes smooth muscles of the uterus.

CRAVINGS

Chromium helps reduce cravings by stabilising blood sugar levels and improving insulin sensitivity.

BREAST TENDERNESS

Magnesium reduces water retention by regulating electrolyte balance, helping alleviate swelling and tenderness.

HEADACHES

Magnesium reduces headaches by preventing the constriction of blood vessels.

Nutrient Delivery Biotechnology

Ingredients with Impact

Magnesium

Chromium

Iron

Chamomile

Omega 3 DHA & EPA

Vitamin B6

Vitamin C

Saffron

Vitamin D3

Zinc

Bio-based Packaging

Frequently Asked Questions

Your Cycle Your Way

Free shipping

FLEXIBLE PLAN

REFERRALS

RISK-FREE

Menstrual health,
matters